Being obese or overweight arises from excess energy consumption, relative to expenditure, over long periods. Although eating patterns are influenced by many factors, such as cultural, social and commercial factors, the regulation of food intake and uptake in the body is a very complex process, which involves biochemical signals and hormones from many sources including the brain-gastrointestinal axis, fat stores and the pancreas. Even the fat cells, adipocytes, themselves are highly specialised to play important roles in energy storage, fatty acid metabolism and glucose regulation. Obesity is also correlated with inflammation in the body and, once overweight or obese, shifting the balance to lose weight may not be as simple as just reducing energy consumption and increasing energy output.
For the full text, click here Weight-Loss-white-paper-May-2016